DSIP 10 mg | Peptide Delta pour le sommeil et la récupération

Molecular mechanism of action: DSIP does not act as a sedative; it acts as a modulator of several regulatory systems via complementary pathways.
(1) Slow-wave sleep—modulation of thalamocortical activity associated with delta waves, without central nervous system depression.
(2) Regulation of the hypothalamic-pituitary-adrenal (HPA) axis: attenuation of CRH and ACTH release, accompanied by a decrease in circulating corticosterone in stress models.
(3) Antinociception—potentiation of the endogenous opioid system (metenkephalin), with documented analgesic effects in animal models.
(4) Neuroendocrine modulation—influence on GH and LH secretion, interaction with somatostatin.
(5) Antioxidant action—reduction of oxidative stress and stabilization of cell membranes.

Search for apps

• Sleep architecture and delta activity (slow waves)
• Regulation of the HPA axis and cortisol (models of chronic stress)
• Antinociception and pain perception threshold
• Physiological recovery and nocturnal secretion of growth hormone (GH)
• Chronobiology and resynchronization of circadian rhythms
• Withdrawal protocols (opioids, alcohol) and withdrawal symptoms
• Neuroprotection and resistance to oxidative stress

Analytical data

• Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE)
• Chemical formula: C35H48N10O15
• Molecular weight: 848.8 Da
• HPLC Purity: $\ge 99\%$ (certified by Janoshik, certificate of analysis available per batch)
• Form: White, sterile, lyophilized powder
• Solubility: Bacteriostatic water, sterile water, physiological saline solution
• Storage of freeze-dried powder: Up to 24 months at -20°C
• Storage after reconstitution: 4 weeks at +4°C, protected from light

10 mg format — For whom?

The 10 mg format corresponds to the reference packaging for DSIP in the scientific literature. Reconstitution with 1 ml of bacteriostatic water yields a concentration of 10 mg/ml, while reconstitution with 2 ml gives a concentration of 2.5 mg/ml, thus facilitating precise sample fractionation. This format is suitable for short- to medium-duration protocols, without exposing the lyophilized powder to unnecessary handling cycles.

Reconstruction and conservation

Reconstitute with sterile or bacteriostatic water (recommended concentration: 2.5 to 5 mg/mL). Inject the solvent along the side of the vial without vigorous shaking: DSIP is sensitive to mechanical stress. The reconstituted solution is stable for 4 weeks at +4°C, protected from light. Unreconstituted lyophilized powder can be stored for up to 24 months at -20°C. Avoid repeated freeze-thaw cycles and prolonged contact with air after reconstitution.